20-(16-Mercaptohexadecanyloxy)-3,6,9,12,15,18-hexaoxaeicosanoic acid. Application: SAM preparation, carboxylate coating, and hydrophilic surface.
Polyethyleneglycols (PEGs) are widely used for material modifications to improve hydrophilicity of the surface. PEG-coated materials are usually more stable under physiological conditions. Since Carboxy-EG6-undecanethiol has 6 ethylene glycol units, 11 carbon Atoms, and an SH group at the end, it can be used to prepare a highly oriented and hydrophilic SAM on a gold surface suitable for biomaterial-labelings on the surface due to the improved hydrophilicity. The hydrophilic surface can prevent proteins or other biomaterials from non-specific binding. Therefore, the SAM prepared by this reagent will provide a better surface to develop biomaterial sensors or DNA/protein microarrays.