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GlykoPrep™ InstantPC, InstantAB and APTS kits for automation on the Agilent Bravo are now available! GlykoPrep™ with InstantPC labelling for MS applications. ProZyme, Inc. and BiOptic, Inc. Sign Licensing Agreement to Develop Gly-Q System for Glycan Analysis Development of an Instant Glycan Labeling Dye for High Throughput Analysis by Mass Spectrometry NEW PRODUCT: ProZyme launches improved 2-AB labeling kit NEW PRODUCT: ProZyme launches alpha(2-6)-Sialyltransferase kit NEW PRODUCT: ProZyme launches beta(1,4)-Galactosyltransferase kit NEW PRODUCT: Rapid-Reductive-Amination™ APTS Labeling now available for GlykoPrep™
Mar 22nd, 2011

GlykoPrep™ Instant AB now fully commercialised

GlykoPrep™ Instant AB is now fully commercialised and the requirement for a CDA/MTA agreement is no longer required.
N-Glycan Sample Preparation

The distribution of N-linked glycans plays a critical role in the efficacy, immunogenicity, and pharmacokinetics of therapeutic proteins. Multi-step, multi-day, sample preparation methods have limited N-linked glycan analysis to only samples that represent critical decision points. Glycan analysis for bioreactor control, strain selection or comparability studies has never been possible.
The GlykoPrep™ platform dramatically streamlines glycoprotein sample preparation. From purification to glycan release and labeling, the entire sample prep can be completed in 3 hours, not 3–4 days.

  • Innovative platform can process up to 192 samples in less tgab 3 hours
  • Modular format enables seamless integration into a variety of workflows
  • Rapid labeling and cleanup for quantitative data

The GlykoPrep Sample Preparation System requires minimal equipment: a centrifuge with a deep-well plate rotor (minimum 44 mm height), a Starter Labware Kit, and Heater and Incubation Blocks.


New glycoanalysis kits coming soon — call us to talk about our new product pipeline!

Flexibility



GlykoPrep is modular and can be integrated into any workflow, regardless of sample throughput or sample type. The GlykoPrep platform is a streamlined solution for anyone that requires rapid, quantitative glycan profiling on your current analysis platform.



Applications


  • Cell culture optimization>
  • Strain selection
  • Product characterization
  • PAT assays for QbD
  • QC release

Sample Types


  • Monoclonal antibodies (purified or crude)
  • Fc-fusion proteins
  • Other recombinant glycoproteins

Analysis


  • HPLC
  • LC/MS
  • CE
  • MS
  • HPAEC-PAD

Automation Options


  • Manual processing
  • Semi-automated with liquid handling system
  • Fully automated

Further Information


  • Contact us for a demonstration of the GlykoPrep Rapid Glycoprotein Sample Preparation Platform


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